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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON2 All Species: 14.85
Human Site: S846 Identified Species: 29.7
UniProt: Q8WXE9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXE9 NP_149095.2 905 101165 S846 T T S A S K A S V R S I S V E
Chimpanzee Pan troglodytes XP_001135210 905 101144 S846 T T S A S K A S V R S I S V E
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 F835 A N R V N V E F S M P T T S A
Dog Lupus familis XP_864856 735 82747 M677 F A T V Q F G M L D T C A S K
Cat Felis silvestris
Mouse Mus musculus Q8BZ60 895 99593 T837 V E F S M P T T S A S K A A V
Rat Rattus norvegicus NP_001129346 895 99472 T837 V E F S M P T T S A S K A A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 L807 K N S G T N Q L L L L A S L T
Chicken Gallus gallus XP_421302 887 99388 T829 V E F D M P T T S A S K A T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 L801 V E V E F D M L S A S A S K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24212 1262 137751 T1187 A T Q V S H T T V R S V S V Q
Honey Bee Apis mellifera XP_396872 1188 129859 T1113 A T Q V S H T T A R S V S F Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 T982 T I E V E Y H T P H T T A S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 31.4 N.A. 86.1 85.8 N.A. 68 69.8 N.A. 48.5 N.A. 23.6 24.7 N.A. 25.5
Protein Similarity: 100 99.6 98 49.5 N.A. 90 89.7 N.A. 76.8 79.8 N.A. 61.7 N.A. 38.7 40 N.A. 44.6
P-Site Identity: 100 100 0 0 N.A. 6.6 6.6 N.A. 13.3 6.6 N.A. 13.3 N.A. 46.6 33.3 N.A. 6.6
P-Site Similarity: 100 100 13.3 33.3 N.A. 26.6 26.6 N.A. 33.3 20 N.A. 13.3 N.A. 66.6 53.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 0 17 0 0 17 0 9 34 0 17 42 17 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 9 0 9 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 34 9 9 9 0 9 0 0 0 0 0 0 0 17 % E
% Phe: 9 0 25 0 9 9 0 9 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 17 9 0 0 9 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 17 0 0 0 % I
% Lys: 9 0 0 0 0 17 0 0 0 0 0 25 0 9 17 % K
% Leu: 0 0 0 0 0 0 0 17 17 9 9 0 0 9 0 % L
% Met: 0 0 0 0 25 0 9 9 0 9 0 0 0 0 0 % M
% Asn: 0 17 0 0 9 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 25 0 0 9 0 9 0 0 0 0 % P
% Gln: 0 0 17 0 9 0 9 0 0 0 0 0 0 0 17 % Q
% Arg: 0 0 9 0 0 0 0 0 0 34 0 0 0 0 0 % R
% Ser: 0 0 25 17 34 0 0 17 42 0 67 0 50 25 0 % S
% Thr: 25 34 9 0 9 0 42 50 0 0 17 17 9 9 9 % T
% Val: 34 0 9 42 0 9 0 0 25 0 0 17 0 25 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _